براءات الاختراع - 2018
براءات الاختراع - 2018م
تمكن بعض باحثي المعهد من الحصول على منح لـ 9 براءات اختراع التالية:
1) براءة اختراع برقم US10151726 B2، مكتب براءات الاختراع الأمريكي، منحت في 11 ديسمبر 2018م، بعنوان:
"Bioimaging nucleic acids, proteins and enzymes"
خالد أبوصلاح، سلمان الركيان وعبدالله مشهور
الملخص : Systems and methods for labeling, staining, and bioimaging of nucleic acids, their fragments, proteins, polypeptides and enzymes are described. In one aspect, a percentage concentration agarose gel or polyacrylamide gel is generated with agarose or polyacrylamide powder respectively. Silicon nanoparticles are added to the agarose or polyacrylamide gel at a required concentration via the agarose or polyacrylamide powder or after agarose or polyacrylamide solubilization in a loading buffer. The nucleic acid is added to agarose gel slots and proteins or enzymes are added to polyacrylamide gel slots in the loading buffer. The loading buffer is then electrophoresed in each case for an amount of time, causing the added silicon nanoparticles or the added ethidium bromide (after agarose solubilization) to generate a bound and labeled nucleic acid and their fragments and proteins or enzymes (with silicon nanoparticles only).
https://patents.google.com/patent/US10151726B2/en
2) براءة اختراع برقم US10138135 B1، مكتب براءات الاختراع الأمريكي، منحت في 27 نوفمبر 2018م، بعنوان:
"Synthesis of titanium dioxide nanoparticles using Origanum majorana herbal extracts"
منال أحمد عوض، عواطف أحمد هندي، خالد مصطفى أورتشي ووضحى خلف العنزي
الملخص : Synthesis of titanium dioxide nanoparticles using Origanum majorana (O. majorana) herbal extracts may be achieved by mixing Titanium (IV) isopropoxide (TTIP) with O. majorana extracts. The O. majorana herbal extracts may be extracts obtained using boiled water. The TTIP may be mixed with the O. majorana extract at a ratio of 2:1. The resulting paste may be heated and pounded into a powder. The powder may then be calcinated in a muffle furnace, producing O. majorana titanium dioxide nanoparticles. The O. majorana titanium dioxide nanoparticles may be efficient photocatalysts..
https://patents.google.com/patent/US10138135B1/en?oq=+US+10%2c138%2c135+B1
3) براءة اختراع برقم US10111441 B1، مكتب براءات الاختراع الأمريكي، منحت في 30 أكتوبر 2018م، بعنوان:
"Synthesis of silver-PMMA nanocomposite film using herbal extract"
منال أحمد عوض، عواطف أحمد هندي، خالد مصطفى أورتشي ودينا وفيق عوض سليمان
الملخص : The synthesis of a silver-PMMA nanocomposite film using herbal extract includes mixing an aqueous extract of Aristolochia bracteolate buds with an aqueous solution of silver nitrate, thereby reducing the silver ions to silver metal nanoparticles. A solution of the silver nanoparticles is added to a solution of PMMA [poly (methyl methacrylate)] in N′N-dimethylformamide (DMF) with stirring at 80° C. A brown solution of silver colloids develops, which is cast in a glass plate and the DMF is evaporated at room temperature, leaving a silver-PMMA nanocomposite film. Testing on water shows the silver-PMMA nanocomposite film prevents or inhibits growth of microbes, suggesting use as an antimicrobial or antibacterial agent, e.g., in water purification. In addition, testing by disc diffusion against E. coli and Bacillus cereus showed zones of inhibition, also suggesting use as an antimicrobial or antibacterial agent.
https://patents.google.com/patent/US10111441B1/en?oq=US+10111441+B1
4) براءة اختراع برقم US10086027 B1، مكتب براءات الاختراع الأمريكي، منحت في 2 أكتوبر 2018م، بعنوان:
"Green synthesis of katononic acid nanosheets"
علي علي حسان الجمال، منال أحمد عوض، رباب الديب، شذا محمد عادل المسراني وعمر أحمد باسويدان
الملخص : The synthesis of katononic acid nanosheets is a method of extraction of katononic acid from the n-hexane fraction of Nuxia oppositifolia. The katononic acid isolated from N. oppositifolia may be suspended in methanol and added dropwise to boiling water, sonicated, stirred, and freeze dried to form katononic acid nanosheets. These katononic acid nanosheets may be used to kill cancer cells or microorganisms.
https://patents.google.com/patent/US10086027B1/en?oq=US+10086027+B1
5) براءة اختراع برقم US10052302 B2، مكتب براءات الاختراع الأمريكي، منحت في 21 أغسطس 2018م، بعنوان:
"Green synthesis of reduced graphene oxide silica nanocomposite using nigella sativa seeds extract"
منال أحمد عوض، عواطف أحمد هندي، خالد مصطفى أورتشي وأمل لاريف
الملخص : The green synthesis of a reduced graphene oxide (rGO) silica (SiO2) nanocomposite using Nigella sativa seed extract includes mixing a quantity of carbon source in an acid solution while stirring to obtain a solution; adding a first oxidant gradually into the solution to oxidize the soot and obtain a first suspension; stirring the first suspension while maintaining a temperature of the suspension to about 35° C.; adding plant seeds extract to the first suspension while raising the temperature of the suspension to about 60° C.; adding a second oxidant to the suspension to form the reduced graphene oxide nanoparticles; isolating the reduced graphene oxide nanoparticles by centrifugation; suspending the reduced graphene oxide nanoparticles in water; adding a solution comprising tetraethyl orthosilicate (TEOS), concentrated aqueous ammonia solution and a plant seeds extract under ultrasonication; and increasing the temperature to about 90° C. to form reduced graphene oxide-silicon dioxide nanocomposite suspension.
https://patents.google.com/patent/US10052302B2/en?oq=+US+10052302+B2
6) براءة اختراع برقم US10028988 B1، مكتب براءات الاختراع الأمريكي، منحت في 24 يوليو 2018م، بعنوان:
"Synthesis of Nuxia oppositifolia nanoparticles"
منال أحمد عوض، رباب عبدالمنعم خليل الديب، شذا محمد عادل المسراني وعلي علي الجمال
الملخص : Synthesis of Nuxia oppositifolia nanoparticles includes providing an extract of Nuxia oppositifolia, dissolving the extract in alcohol to provide a mixture, adding water to the mixture to provide an aqueous solution, adding an acidic solution to the aqueous solution to form a final solution including Nuxia oppositifolia nanoparticles; and centrifuging the final solution to isolate the Nuxia oppositifolia nanoparticles.
https://patents.google.com/patent/US10028988B1/en?oq=US+10%2c028%2c988+B1
7) براءة اختراع برقم US9974750B1، مكتب براءات الاختراع الأمريكي، منحت في 22 مايو 2018م، بعنوان:
"Synthesis of ifflaionic acid nanoparticles"
شاذا محمد عادل المسراني، رباب عبدالمنعم خليل الديب، علي علي الجمال ومنال أحمد عوض
الملخص : Synthesis of ifflaionic acid nanoparticles includes dissolving a powder of ifflaionic acid in an alcohol solution to form a first solution, adding the first solution to an aqueous solution under ultrasonic conditions to produce a sonicated solution, stirring the sonicated solution for a duration of time to produce a mixture, and freeze-drying the mixture to provide the ifflaionic acid nanoparticles.
https://patents.google.com/patent/US9974750B1/en
8) براءة اختراع برقم US9974749 B2، مكتب براءات الاختراع الأمريكي، منحت في 22 مايو 2018م، بعنوان:
"Method of treating diabetic wounds using biosynthesized nanoparticles"
منال أحمد عوض، عواطف أحمد هندي، مي عبدالرحمن العبيد وقيع الله، برومي فيرك وخالد مصطفى أورتشي
الملخص : The method of treating diabetic wounds using biosynthesized nanoparticles includes administering an effective amount of silver and gold nanoparticles to a patient in need thereof. The silver and gold nanocomposite is prepared by ‘biosynthesis”, i.e., by providing a first aqueous solution of a noble metal salt or a noble metal oxide; providing a second solution of an aqueous plant extract, and combining the first solution and the second solution to produce a solution including nanoparticles of the noble metal. The second solution includes a plant extract obtained from Solenostemma argel, Trigonella foenum-graecum and Cinnamomum cassia. The metal salt can include silver nitrate (AgNO3) and chloroauric acid (HAuCl4). Nanoparticles of gold and nanoparticles of silver are prepared separately, and then mixed to obtain a composition containing a gold and silver nanocomposite.
https://patents.google.com/patent/US9974749B2/en?oq=US+9%2c974%2c749+B2
9) براءة اختراع برقم US9889170 B1، مكتب براءات الاختراع الأمريكي، منحت في 13 فبراير 2018م، بعنوان:
"Synthesis of Nanoparticles using Balanites Aegyptiaca"
منال أحمد عوض، رباب عبدالمنعم خليل الديب، د. عواطف هندي، شاذا محمد عادل المسراني، وخالد أورتشي
الملخص : A method of preparing nanoparticles from desert date can include providing a metal salt solution comprising metal ions; providing desert date extract solution that comprises a reducing agent, and combining the metal ion solution and the desert date extract solution while stirring at a temperature in the range of 25° C. to 100° C. to produce metal or metal oxide nanoparticles. The metal nanoparticles can be gold nanoparticles. The metal oxide nanoparticles can be zinc oxide nanoparticles. The nanoparticles can be used to inhibit the growth or proliferation of a cancer cell and/or microorganisms.
